Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Contact with water or acid causes release of hydrazoic acid hn. The decomposition temperatures of the alkali metal azides are. This material contains potassium permanganate listed as manganese compounds, n. Over a period of time, sodium azide may react with copper, lead, brass, or solder in plumbing systems to form an accumulation of the highly explosive compounds of lead azide and copper azide. Sodium azide definition of sodium azide by medical. It is used for the preparation of other azide compounds. Sodium azide definition of sodium azide by medical dictionary. Download msds pdf search msds currently available for download bioworld offers sodium azide 10% for your research at low price. Materials to avoid halogenated hydrocarbon, metals, acids, acid chlorides hazardous decomposition products. However, due to the composition and volume of this product, combustion products generated from it are not expected to present a significant hazard. Safety data sheet according to 29cfr19101200 and ghs rev. Material safety data sheet sodium azide msds section 1. Sodium azide nan3, a common bactericide, pesticide and industrial nitrogen gas generator is known to be highly mutagenic in several organisms including plants and animals.
This can also create a dangerous situation when azide solutions are disposed down the drain into the sanitary sewer system. Sodium azide is commonly used as a bacteriostatic preservative for biological samples and also as a source to generate gas in automobile airbags. When it is mixed with water or an acid, sodium azide changes rapidly to a toxic gas with a pungent sharp odor. Central drug house p ltd 728 vardaan house new delhi2. Sodium azide is a known inhibitor of cytochrome c oxidase in mitochondoria and decreases atp generation 2022, resulting in the disruption of cellular activities which require atp. The effect of sodium azide on the gas metabolism of b. Sodium azide material safety data sheet cas no 26628228 sds. Material safety data sheet for reagents containing sodium azide. It acts as a precursor to prepare inorganic azides like lead azide and silver azide. Upon heating or upon irradiation with ultraviolet light, it decomposes into potassium metal and nitrogen gas.
Sodium azide is the inorganic compound with the formula nan 3. It also changes into a toxic gas hydrazoic acid when it comes in contact with solid metals for example, when it is poured into a. Chemical product and company identification product name. Sodium nitrite material safety data sheet cas no 7632. Ingestion is an important route of exposure to solid sodium azide. However, we make no warranty of merchantibility or any other. Sodium azide is a white crystalline solid that is highly toxic when ingested or inhaled. When it hits water, it turns into an acid that can eat through your skin. Sodium nitrite to the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Sodium nitrite liver irregularities based on human evidencesodium nitrite section 12.
Al though industrial exposure is common, fatal ingestion is rare, we describe the case of a 30yearold man who ingested 15 to 20 g of sodium azide. The number of electrons in each of potassiums shells is 2, 8, 8, 1 and its electron configuration is ar 4s 1. Potassium was discovered and first isolated by sir humphrey davy in 1807. The tpq does not default to 0 pounds for nonpowder, nonmolten, nonsolution form.
Lithium is stable in contact with dry bromine, but heavy impact will initiate explosion, while sodium in contact with bromine needs only moderate impact for initiation. Studies of the effect of sodium azide on microbic growth and respiration. Sodium azide is a white powder that explodes when it hits metal. Case report ingestion, azide, toxicity suicidal sodium azide ingestion sodium azide nan9 is a highly reactive, toxic, widely used chemical.
Potassium ignites in bromine vapor and explodes violently in contact with liquid bromine and rubidium. Sodium azide appears as a colorless crystalline solid. Mar 28, 2005 toxic syndrome description sodium azide the purpose of this document is to enable health care workers and public health officials to recognize an unknown or suspected exposure to sodium azide. Sodium azide solutions will react with metals to form metal azides, which can be shock sensitive and explosive.
Potassium is the seventh most abundant element on earth. Potassium hydroxide 10583 no lb rq lb final rq 454 kg no no potassium iodide 7681110 no no no no no sodium azide 26628228 sodium azide no lb final rq. Sodium azide material safety data sheet cas no 26628228. Baylishillman acetates such as ethyl 2 acetoxyphenylmethylac rylate can undergo nucleophilic displacement by sodium. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Cultured cells were damaged and detached from culture surfaces when sodium azide over 10 mm. This material does not contain any hazardous air pollutants. It also changes into a toxic gas hydrazoic acid when it comes in contact with solid metals for examp. Remove contaminated clothing and wash before reuse. This material does not contain any class 1 ozone depletors. Sodium azide upon thermal decomposition may emit toxic gases, including nitrogen oxides. A 1% aqueous solution of sodium azide 154mm for use as a preservative for laboratory reagents. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
If sodium azide is released into the air as fine particles aerosol, it has the potential to contaminate agricultural products. It is highly toxic and presents a severe explosion risk when shocked or heated. This should be considered when choosing a container for sodium azide solutions. In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Sodium azide is used in organic synthesis for the introduction of an azide group to prepare a desired compound. Due to the hazards associated with solid sodium azide, buying dilute solutions of 5% or less sodium azide is recommended.
The tpq does not default to 0 pounds for nonpowder, nonmolten, nonsolution form no. It is also a metabolic inhibitor, which inhibits oxidative phosphorylation. Toxic syndrome description sodium azide the purpose of this document is to enable health care workers and public health officials to recognize an unknown or suspected exposure to sodium azide. It is an ionic substance, is highly soluble in water, and is very acutely toxic. Sodium azide, 1% wv, aqueous solution, common lab preservative. Determination of azide in aqueous samples by ion chromatography with suppressed conductivity detection. Cas 10583 26628228 7681110 7166,alkaline potassium iodide azidesee other information potassium hydroxide sodium azide potassium iodide msds toxicity property. Sodium azide hazards and disposal sodium azide is used at uno in the preservation of samples and stock solutions. The salt readily dissolves in water to yield the azide anion n3. Nan 3 microbiology a toxic salt addedconcentration, 0.
Material safety data sheet for reagents containing sodium. Evacuate all nonessential personnel from area and ventilate. Graphical abstract a simple and efficient method for the diazotization and azidation of different aromatic amines over cellulose sulphoric acid, sodium nitrite and sodium azide under mild. In airbag inflation, as a preservative in diagnostic medicinals.
Sodium azide is the nastiest chemical that ever saved lives. An explosion occurred when a mixture of sodium azide, methylene chloride, dimethyl sulfoxide, and sulfuric acid were being concentrated on a rotary evaporator. Our msds database is an easy to use, do it yourself tool, and best of all. Consult the safety data sheet sds and these other resources. Burns in air and may explode if large quantities are involved. Hemacolor solution 2, fixative hemacolor solution 2, fixative 65044b page. It has a role as a mutagen, an antibacterial agent and an explosive. Sodium azide can be absorbed into the body by inhalation, ingestion, skin contact, or eye contact. Sodium azide is a rapidly acting, potentially lethal chemical that exists as an odorless, white crystalline solid. Our team of scientists has experience in all areas of research including life science, material science, chemical synthesis, chromatography, analytical and many others. It is often a better choice for this purpose than thimerosal, as. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Ready to use pbs with azide buffer is a solution with a phosphate buffer concentration of 0. Sodium azide nan3 is a colorless crystalline solid and is readily soluble in water.
The number of electrons in each of potassium s shells is 2, 8, 8, 1 and its electron configuration is ar 4s 1. The use of the 1% solution is convenient and minimizes exposure and contamination risks normally encountered while handling sodium azide powder. Sodium azide is the sodium salt of hydrogen azide hydrazoic acid. View product specific information, msds, references and buying faq. The effect of sodium azide on cell detachment was investigated to clarify the role of cell metabolism in cell detachment. It is often a better choice for this purpose than thimerosal, as sodium azide does not contain mercury. It is soluble in water or liquid ammonia, slightly soluble in alcohols, and insoluble in ether. Regulatory information osha hazards target organ effect, highly toxic by ingestion, highly toxic by skin absorption sara 302 components the following components are subject to reporting levels established by sara title iii, section 302. Sodium azide nan3 a potent metallic poison, potassium nitrate kno3, silicon dioxide sio2, which are secondary reactants, nitrogen gas n2, which rapidly fills the air bag. Alkaline iodide azide solution i safety data sheet according to federal register vol.530 415 797 610 600 535 284 136 954 812 521 1021 1170 904 31 1235 42 724 1310 950 1428 702 1186 1371 116 1253 91 413 1393 333 323 764 1506 1345 629 721 365 990 1355 780 1068 441 803 1475 295